ELISpot

Applications

Screening of antibody producing cells
Serial check on immune reactions towards chemicals, and newly developed pharmaceuticals
Optimization of anti-tumour activities of dendritic cells and T-lymphocytes
Control of guided vaccinations, e.g. HIV
Diagnosis and prognostic analysis of autoimmune diseases, e.g. Diabetes, Multiple Sclerosis
     or Rheumatoid Arthritis
Monitoring of immune therapy
Control of de-sensibilization treatment of allergic diseases
Prediction of rejection crisis in organ transplantation
Analysis of stem cell function
Determination of transfection efficacy in gene therapy
Measuring secretory products of low frequency tissue, tumour and immune cells

Information

ELISpot (enzyme-linked immunosorbent spot) assays are highly sensitive immunoassays that measure the frequency of antigen-specific T cells by measuring the number of cytokine-secreting cells within the blood at a single cell level.

Therapeutics

Vaccines, CAR-T, BCMA therapeutics, TCR, Gene therapy, siRNA, Oligonucleotides, mRNA vaccines.