Cell & Gene Therapy

Solutions

  • Pharmacokinetics (PK) & Biodistribution
    • Branched DNA
    • Quantitative PCR (qPCR)
    • Ligand binding assays
  • Immunogenicity
    • Ligand binding assays
    • Cell-based Nab assay
    • ELISpot assay
  • Biomarker Assays
    • Inflammation (e.g. IL-6, MCP)
    • Tissue Damage (e.g. CRP, LDH)
    • Surface Antigen (e.g. CD22, CD138)

Bioanalytical Assays to Support Cell and Gene Therapy Solutions

The bioanalysis of cell and gene therapies requires more than what traditional chromatographic or ligand-binding methods can offer. These highly complex therapies require bioanalytical scientists with expertise in molecular biology and immunogenicity methodologies, both ligand binding and cell-based assays, flow cytometry and ELISpot in a regulated (GxP) environment.

Somru Scientists have deep scientific expertise and regulatory knowledge to develop robust and novel bioanalytical methods (e.g., molecular , assays, immunoassay and cell-based assays) to support biodistribution, safety, efficacy, and immunogenicity of innovative cell and gene therapeutic candidates.

Validated Ready to Use Anti- AAV Immunogenicity Assays

Somru is currently developing off-the-shelf assays to evaluate the immunogenicity of the AAV vectors using both ligand binding method, cell-based Nab methods, and ELISpot assays. Please contact us to learn more about the specific details on the development effort.

 

We can help you harness the power of gene therapy quickly and cost-effectively.

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